The nonvesicular sterol transporter Aster-C plays a minor role in whole body cholesterol balance

The nonvesicular sterol transporter Aster-C plays a minor role in whole body cholesterol balance

Introduction:The Aster-C protein (encoded by the Gramd1c gene) is an endoplasmic reticulum (ER) resident protein that has been reported to transport cholesterol from the plasma membrane to the ER. Although there is a clear role for the closely-related Aster-B protein in cholesterol transport and dow...

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Bibliographic Details
Main Authors: Rakhee Banerjee, Rachel C. Hohe, Shijie Cao, Bryan M. Jung, Anthony J. Horak, Iyappan Ramachandiran, William J. Massey, Venkateshwari Varadharajan, Natalie I. Zajczenko, Amy C. Burrows, Sumita Dutta, Maryam Goudarzi, Kala Mahen, Abigail Carter, Robert N. Helsley, Scott M. Gordon, Richard E. Morton, Christopher Strauch, Belinda Willard, Camelia Baleanu Gogonea, Valentin Gogonea, Matteo Pedrelli, Paolo Parini, J. Mark Brown
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Physiology
Subjects:
cholesterol
lipoprotein
metabolism
steroid hormone
oxysterol
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2024.1371096/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2024.1371096/full

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