The effect of dapagliflozin on uric acid excretion and serum uric acid level in advanced CKD

Abstract Sodium–glucose cotransporter 2 inhibitors (SGLT2i) exhibit renoprotective effect in patients with chronic kidney disease (CKD) and reduce serum uric acid (UA) in patients with diabetes mellitus. However, it is not clarified whether SGLT2i reduce serum UA levels in patients with advanced CKD...

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Bibliographic Details
Main Authors: Yukimasa Iwata, Shoki Notsu, Yushi Kawamura, Waka Mitani, Shinjiro Tamai, Madoka Morimoto, Masafumi Yamato
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-32072-y