The effect of dapagliflozin on uric acid excretion and serum uric acid level in advanced CKD

The effect of dapagliflozin on uric acid excretion and serum uric acid level in advanced CKD

Abstract Sodium–glucose cotransporter 2 inhibitors (SGLT2i) exhibit renoprotective effect in patients with chronic kidney disease (CKD) and reduce serum uric acid (UA) in patients with diabetes mellitus. However, it is not clarified whether SGLT2i reduce serum UA levels in patients with advanced CKD...

Full description

Bibliographic Details
Main Authors:	Yukimasa Iwata, Shoki Notsu, Yushi Kawamura, Waka Mitani, Shinjiro Tamai, Madoka Morimoto, Masafumi Yamato
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-03-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-023-32072-y

Similar Items

Association between urinary uric acid excretion and kidney outcome in patients with CKD
by: Yuta Asahina, et al.
Published: (2024-03-01)

Uric acid transporters BCRP and MRP4 involved in chickens uric acid excretion
by: Xuedong Ding, et al.
Published: (2019-05-01)

Urine alkalization facilitates uric acid excretion
by: Seyama Issei, et al.
Published: (2010-10-01)

Electrochemical analysis of uric acid excretion to the intestinal lumen: Effect of serum uric acid-lowering drugs and 5/6 nephrectomy on intestinal uric acid levels.
by: Kyoko Fujita, et al.
Published: (2019-01-01)

Carnosine reduces serum uric acid in hyperuricemia rats via restoring hepatorenal dysfunction and enhancing uric acid excretion by inhibiting inflammation
by: Ming Chen, et al.
Published: (2023-11-01)

Population-specific factors associated with fractional excretion of uric acid
by: Ravi K. Narang, et al.
Published: (2019-11-01)

Diabetic nephropathy with marked extra-capillary cell proliferation: a case report
by: Madoka Morimoto, et al.
Published: (2023-05-01)

Goose astrovirus infection affects uric acid production and excretion in goslings
by: Wankun Wu, et al.
Published: (2020-04-01)

Disparity of serum uric acid threshold for CKD among hypertensive and non-hypertensive individuals
by: Bowen Zhu, et al.
Published: (2024-12-01)

Effect of urine pH changed by dietary intervention on uric acid clearance mechanism of pH-dependent excretion of urinary uric acid
by: Kanbara Aya, et al.
Published: (2012-06-01)

Effect of Eurycoma longifolia Stem Extract on Uric Acid Excretion in Hyperuricemia Mice
by: Ruixia Bao, et al.
Published: (2019-12-01)

Uric Acid and the Heart
Published: (2005-01-01)

Uric Acid and the Heart.
Published: (2005-03-01)

High uric acid or low uric acid which is better for hemodialysis patients?
by: Wenyun Wang, et al.
Published: (2020-01-01)

The Time-Feature of Uric Acid Excretion in Hyperuricemia Mice Induced by Potassium Oxonate and Adenine
by: Shaoshi Wen, et al.
Published: (2020-07-01)

Effects of dapagliflozin on serum and urinary uric acid levels in patients with type 2 diabetes: a prospective pilot trial
by: Tao Yuan, et al.
Published: (2020-10-01)

Serum uric acid and leg ulcers
by: Rodrigo Araldi Nery, et al.
Published: (2019-07-01)

The Role of Serum Uric Acid in Preeclampsia
by: Amir Taefi, et al.
Published: (2008-09-01)

Serum uric acid in children and adolescents
by: Nilton Rosini, et al.
Published: (2018-02-01)

POS-304 EFFECT OF URIC ACID LOWERING THERAPY ON THE PROGRESSION OF CKD: RETROSPECTIVE TUNISIAN STUDY
by: M. Ben Salem, et al.
Published: (2021-04-01)

Serum uric acid levels are associated with homeostasis model assessment in obese nondiabetic patients: HOMA and uric acid
by: Cesar I. Elizalde-Barrera, et al.
Published: (2017-10-01)

The Association of Urinary Sodium and Potassium with Renal Uric Acid Excretion in Patients with Chronic Kidney Disease
by: Fengqin Li, et al.
Published: (2018-08-01)

Hyponatremia with Persistent Elevated Urinary Fractional Uric Acid Excretion: Evidence for Proximal Tubular Injury?
by: S.-M.Kurt Lee, et al.
Published: (2016-08-01)

Genome-wide Association Study of 24-Hour Urinary Excretion of Calcium, Magnesium, and Uric Acid
by: Erin B. Ware, PhD, MPH, et al.
Published: (2019-12-01)

Tubular Handling of Uric Acid and Factors Influencing Its Renal Excretion: A Short Review
by: Tubular Handling of Uric Acid and Factors Influencing Its Renal Excretion: A Short Review, et al.
Published: (2016-07-01)

The effect of uric acid and urinary sodium excretion on prehypertension: a nationwide population-based study
by: Shina Lee, et al.
Published: (2020-05-01)

Role of Uric Acid in Semen
by: Saleem Ali Banihani
Published: (2018-07-01)

Food alkalization and uric acid
by: Đorđević Jelena
Published: (2018-01-01)

Uric Acid and Arterial Stiffness
by: Albu A, et al.
Published: (2020-01-01)

STUDY OF URIC ACID IN IRAN
by: K. Montazemi, et al.
Published: (1979-03-01)

Reduced serum uric acid levels in neuromyelitis optica: serum uric acid levels are reduced during relapses in NMO.
by: Min, J, et al.
Published: (2012)

Correlation of Serum Uric Acid and Serum Uric Acid/Creatinine Ratio Levels with Adverse Pregnancy Outcomes in Late Pregnancy
by: ZHAO Ru, HAN Chen, HUANG Zeyu, WANG Qian, HU Jun, GE Zhijuan, BI Yan, SHEN Shanmei
Published: (2024-03-01)

Difference between uric acid stones and non-uric acid stones in conventional CT scanning
by: LIU Huan, YANG Xue-dong, SHI Feng-xiang, WU Zhe, SUN Hao, JIN Zheng-yu
Published: (2021-06-01)

Association of uric acid and uric acid to creatinine ratio with chronic kidney disease in hypertensive patients
by: Nathalia Rabello Silva, et al.
Published: (2021-09-01)

Urine Glucose Excretion Attenuates the Association Between Lipid Accumulation Product and Serum Uric Acid in Subjects with Prediabetes
by: Chen J, et al.
Published: (2020-06-01)

Effects of Oligonol®, an oligomerized polyphenol formulated from lychee fruit, on serum concentration and urinary excretion of uric acid
by: Yuji Moriwaki, et al.
Published: (2011-01-01)

Serum Uric Acid Levels in Schizoaffective Disorder
by: Aslı Kazgan Kılıçaslan, et al.
Published: (2022-06-01)

Serum uric acid levels in patients with psoriasis
by: Ghiasi M, et al.
Published: (2012-04-01)

Serum uric acid a depression biomarker.
by: Xiandong Meng, et al.
Published: (2020-01-01)

Is Dapagliflozin future for CKD?
by: Yumna Zafar, et al.
Published: (2022-02-01)