Characterizing intergenic transcription at RNA polymerase II binding sites in normal and cancer tissues

Characterizing intergenic transcription at RNA polymerase II binding sites in normal and cancer tissues

Summary: Intergenic transcription in normal and cancerous tissues is pervasive but incompletely understood. To investigate this, we constructed an atlas of over 180,000 consensus RNA polymerase II (RNAPII)-bound intergenic regions from 900 RNAPII chromatin immunoprecipitation sequencing (ChIP-seq) e...

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Bibliographic Details
Main Authors: Pierre de Langen, Fayrouz Hammal, Elise Guéret, Jean-Christophe Mouren, Lionel Spinelli, Benoit Ballester
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Cell Genomics
Subjects:
enhancers
non-coding DNA
regulatory genomics
intergenic
RNA Polymerase II
gene regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2666979X23002252

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http://www.sciencedirect.com/science/article/pii/S2666979X23002252

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