Evolutionary Conservation of Mechanical Strain Distributions in Functional Transitions of Protein Structures
One of the tenets of molecular biology is that dynamic transitions between three-dimensional structures determine the function of proteins. Therefore, it seems only natural that evolutionary analysis of proteins, presently based mainly on their primary sequence, needs to shift its focus toward their...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
American Physical Society
2024-03-01
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| Series: | Physical Review X |
| Online Access: | http://doi.org/10.1103/PhysRevX.14.011042 |