Effect of guanylin peptides on pancreas steatosis and function in experimental diet-induced obesity and after bariatric surgery

Effect of guanylin peptides on pancreas steatosis and function in experimental diet-induced obesity and after bariatric surgery

IntroductionObesity contributes to ectopic fat deposition in non-adipose organs, including the pancreas. Pancreas steatosis associates with inflammation and β-cell dysfunction, contributing to the onset of insulin resistance and type 2 diabetes. An improvement of pancreatic steatosis and indices of...

Full description

Bibliographic Details
Main Authors: Aarón Otero, Sara Becerril, Marina Martín, Javier A. Cienfuegos, Víctor Valentí, Rafael Moncada, Victoria Catalán, Javier Gómez-Ambrosi, María A. Burrell, Gema Frühbeck, Amaia Rodríguez
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Endocrinology
Subjects:
uroguanylin
guanylin
guanylate cyclase 2C
β-cell function
lipogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1185456/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1185456/full

Similar Items