Development of ONT-cappable-seq to unravel the transcriptional landscape of Pseudomonas phages

Development of ONT-cappable-seq to unravel the transcriptional landscape of Pseudomonas phages

RNA sequencing has become the method of choice to study the transcriptional landscape of phage-infected bacteria. However, short-read RNA sequencing approaches generally fail to capture the primary 5′ and 3′ boundaries of transcripts, confounding the discovery of key transcription initiation and ter...

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Bibliographic Details
Main Authors: Leena Putzeys, Maarten Boon, Eveline-Marie Lammens, Konstantin Kuznedelov, Konstantin Severinov, Rob Lavigne
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Long-read transcriptomics
Nanopore sequencing
Pseudomonas aeruginosa
Bacteriophages
Transcription regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022001908

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http://www.sciencedirect.com/science/article/pii/S2001037022001908

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