Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli

Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli

Abstract Bacterial meningitis remains a leading cause of infection-related mortality worldwide. Although Escherichia coli (E. coli) is the most common etiology of neonatal meningitis, the underlying mechanisms governing bacterial blood-brain barrier (BBB) disruption during infection remain elusive....

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Bibliographic Details
Main Authors: Ruicheng Yang, Xinyi Wang, Hulin Liu, Jiaqi Chen, Chen Tan, Huanchun Chen, Xiangru Wang
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cell Communication and Signaling
Subjects:
Meningitic E. Coli
Blood-brain barrier
Early growth response 1
Permeability
Neuroinflammation
Online Access:https://doi.org/10.1186/s12964-024-01488-y

Internet

https://doi.org/10.1186/s12964-024-01488-y

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