HDP-a novel heme detoxification protein from the malaria parasite.

When malaria parasites infect host red blood cells (RBC) and proteolyze hemoglobin, a unique, albeit poorly understood parasite-specific mechanism, detoxifies released heme into hemozoin (Hz). Here, we report the identification and characterization of a novel Plasmodium Heme Detoxification Protein (...

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Bibliographic Details
Main Authors: Dewal Jani, Rana Nagarkatti, Wandy Beatty, Ross Angel, Carla Slebodnick, John Andersen, Sanjai Kumar, Dharmendar Rathore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18437218/?tool=EBI