Structural Abnormalities of the Optic Nerve and Retina in Huntington’s Disease Pre-Clinical and Clinical Settings

Huntington’s disease (HD) is a fatal neurodegenerative disorder caused by a polyglutamine expansion in the huntingtin protein. HD-related pathological remodelling has been reported in HD mouse models and HD carriers. In this study, we studied structural abnormalities in the optic nerve by employing...

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Bibliographic Details
Main Authors: Iwona Mazur-Michałek, Katarzyna Kowalska, Daniel Zielonka, Marta Leśniczak-Staszak, Paulina Pietras, Witold Szaflarski, Mark Isalan, Michal Mielcarek
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/10/5450