Surfactant-assisted one-pot sample preparation for label-free single-cell proteomics

Surfactant-assisted one-pot sample preparation for label-free single-cell proteomics

Tsai, Zhang, Scholten et al. develop a surfactant- assisted one-pot sample preparation coupled with mass spectrometry method (SOP-MS) for label-free global single-cell proteomics. This method allows researchers to measure hundreds of proteins from single human cells, suggesting its utility for quant...

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Bibliographic Details
Main Authors: Chia-Feng Tsai, Pengfei Zhang, David Scholten, Kendall Martin, Yi-Ting Wang, Rui Zhao, William B. Chrisler, Dhwani B. Patel, Maowei Dou, Yuzhi Jia, Carolina Reduzzi, Xia Liu, Ronald J. Moore, Kristin E. Burnum-Johnson, Miao-Hsia Lin, Chuan-Chih Hsu, Jon M. Jacobs, Jacob Kagan, Sudhir Srivastava, Karin D. Rodland, H. Steven Wiley, Wei-Jun Qian, Richard D. Smith, Ying Zhu, Massimo Cristofanilli, Tao Liu, Huiping Liu, Tujin Shi
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01797-9

Internet

https://doi.org/10.1038/s42003-021-01797-9

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