The implication of necroptosis-related lncRNAs in orchestrating immune infiltration and predicting therapeutic efficacy in colon adenocarcinoma: an integrated bioinformatic analysis with preliminarily experimental validation

The implication of necroptosis-related lncRNAs in orchestrating immune infiltration and predicting therapeutic efficacy in colon adenocarcinoma: an integrated bioinformatic analysis with preliminarily experimental validation

Background: Necroptosis contributes significantly to colon adenocarcinoma (COAD). We aim to assess the relationship between immunoinfiltration and stemness in COAD patients through the development of a risk score profile using necroptosis-related long noncoding RNAs (NRLs).Methods: Our study was bas...

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Bibliographic Details
Main Authors: Shizhe Li, Xiaotong Wang, Yajun Liu, Junbo Xiao, Jun Yi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Genetics
Subjects:
necroptosis-related genes and lncRNAs
colon adenocarcinoma
stemness
bioinformatic analysis and experimental validation
immune infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1170640/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1170640/full

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