Interleukin-13 and its receptor are synaptic proteins involved in plasticity and neuroprotection

Interleukin-13 and its receptor are synaptic proteins involved in plasticity and neuroprotection

Il-13 is expressed in neurons and IL-13 ko causes memory impairment. Here, authors show that IL-13 and its receptor IL-13Ra1 are pre- and post-synaptic proteins, respectively, involved in synaptic signaling, plasticity and neuroprotection.

Bibliographic Details
Main Authors: Shun Li, Florian olde Heuvel, Rida Rehman, Oumayma Aousji, Albrecht Froehlich, Zhenghui Li, Rebecca Jark, Wanhong Zhang, Alison Conquest, Sarah Woelfle, Michael Schoen, Caitlin C. O´Meara, Richard Lee Reinhardt, David Voehringer, Jan Kassubek, Albert Ludolph, Markus Huber-Lang, Bernd Knöll, Maria Cristina Morganti-Kossmann, Marisa M. Brockmann, Tobias Boeckers, Francesco Roselli
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-35806-8

Internet

https://doi.org/10.1038/s41467-023-35806-8

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