High-Capacity Mesoporous Silica Nanocarriers of siRNA for Applications in Retinal Delivery

The main cause of subretinal neovascularisation in wet age-related macular degeneration (AMD) is an abnormal expression in the retinal pigment epithelium (RPE) of the vascular endothelial growth factor (VEGF). Current approaches for the treatment of AMD present considerable issues that could be over...

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Bibliographic Details
Main Authors: Amelia Ultimo, Mar Orzaez, Maria J. Santos-Martinez, Ramón Martínez-Máñez, María D. Marcos, Félix Sancenón, Eduardo Ruiz-Hernández
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/3/2753