Laser microdissection, proteomics, and multiplex immunohistochemistry: a bumpy ride into the study of paraffin-embedded fetal and pediatric lung tissues

BackgroundKnowledge about lung development or lung disease is mainly derived from data extrapolated from mouse models. This has obvious drawbacks in developmental diseases, particularly due to species differences. Our objective is to describe the development of complementary analysis methods that wi...

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Bibliographic Details
Main Authors: Luis M. Cardoso dos Santos, Yannick Avila, Domitille Schvartz, Anne-Laure Rougemont, Marie-Luce Bochaton-Piallat, Isabelle Ruchonnet-Metrailler
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1191205/full