A review of the clinical experience with CMN-001, a tumor RNA loaded dendritic cell immunotherapy for the treatment of metastatic renal cell carcinoma

A review of the clinical experience with CMN-001, a tumor RNA loaded dendritic cell immunotherapy for the treatment of metastatic renal cell carcinoma

Engineering dendritic cells (DCs) to treat cancer is a long sought-after goal for cell-based immunotherapies. In this review, we focus on the experience with CMN-001, formally AGS-003, a DC-based immunotherapy, employing autologous DC electroporated with autologous tumor RNA to treat subjects with m...

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Bibliographic Details
Main Authors: Mark DeBenedette, Alicia Gamble, Marcus Norris, Joe Horvatinovich, Charles A. Nicolette
Format: Article
Language:English
Published: Taylor & Francis Group 2023-08-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
dendritic cells
mrcc
memory t cells
cancer vaccines
immunotherapy
Online Access:http://dx.doi.org/10.1080/21645515.2023.2220629

Internet

http://dx.doi.org/10.1080/21645515.2023.2220629

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