Tanshinone I attenuates fibrosis in fibrotic kidneys through down-regulation of inhibin beta-A

Abstract Background Tanshinone I (Tan-I), an ingredient of Salvia miltiorrhiza, displays protective effects in several disease models. We aim to study the effect of Tan-I on renal fibrosis and explore its underlining mechanism. Methods Rat renal fibroblasts (NRK-49F) were used as an in vitro model t...

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Bibliographic Details
Main Authors: Ming Wu, Feng Yang, Di Huang, Chaoyang Ye
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Online Access:https://doi.org/10.1186/s12906-022-03592-3