A Mechanistic Understanding of Axon Degeneration in Chemotherapy-Induced Peripheral Neuropathy

A Mechanistic Understanding of Axon Degeneration in Chemotherapy-Induced Peripheral Neuropathy

Chemotherapeutic agents cause many short and long term toxic side effects to peripheral nervous system (PNS) that drastically alter quality of life. Chemotherapy-induced peripheral neuropathy (CIPN) is a common and enduring disorder caused by several anti-neoplastic agents. CIPN typically presents w...

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Bibliographic Details
Main Authors: Yusuke Fukuda, Yihang Li, Rosalind A. Segal
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Neuroscience
Subjects:
axon
chemotherapy
CIPN
degeneration
DRG
neuropathy
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00481/full

Internet

http://journal.frontiersin.org/article/10.3389/fnins.2017.00481/full

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