PGC-1α Promoter Methylation in Parkinson's Disease.

PGC-1α Promoter Methylation in Parkinson's Disease.

The etiopathogenesis of sporadic Parkinson's disease (PD) remains elusive although mitochondrial dysfunction has long been implicated. Recent evidence revealed reduced expression of peroxisome proliferator-activated receptor gamma coactivator-1 α (PGC-1α) and downstream regulated nuclear encode...

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Bibliographic Details
Main Authors: Xiaomin Su, Yaping Chu, Jeffrey H Kordower, Bin Li, Hong Cao, Liang Huang, Maki Nishida, Lei Song, Difei Wang, Howard J Federoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4552803?pdf=render

Internet

http://europepmc.org/articles/PMC4552803?pdf=render

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