Streptococcus pneumoniae Rapidly Translocate from the Nasopharynx through the Cribriform Plate to Invade the Outer Meninges

Streptococcus pneumoniae Rapidly Translocate from the Nasopharynx through the Cribriform Plate to Invade the Outer Meninges

ABSTRACT The entry routes and translocation mechanisms of microorganisms or particulate materials into the central nervous system remain obscure We report here that Streptococcus pneumoniae (pneumococcus), or polystyrene microspheres of similar size, appear in the meninges of the dorsal cortex of mi...

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Bibliographic Details
Main Authors: Teerawit Audshasai, Jonathan A. Coles, Stavros Panagiotou, Shadia Khandaker, Hannah E. Scales, Morten Kjos, Murielle Baltazar, Julie Vignau, James M. Brewer, Aras Kadioglu, Marie Yang
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:mBio
Subjects:
cribriform plate
inflammation
nose-to-meninges translocation
Streptococcus pneumoniae
central nervous system
infectious disease
Online Access:https://journals.asm.org/doi/10.1128/mbio.01024-22

Internet

https://journals.asm.org/doi/10.1128/mbio.01024-22

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