The serine protease inhibitor serpinE2 is a novel target of ERK signaling involved in human colorectal tumorigenesis
<p>Abstract</p> <p>Background</p> <p>Among the most harmful of all genetic abnormalities that appear in colorectal cancer (CRC) development are mutations of KRAS and its downstream effector BRAF as they result in abnormal extracellular signal-related kinase (ERK) signal...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-10-01
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Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/9/1/271 |