Girdin Promotes Tumorigenesis and Chemoresistance in Lung Adenocarcinoma by Interacting with PKM2

Girdin Promotes Tumorigenesis and Chemoresistance in Lung Adenocarcinoma by Interacting with PKM2

Girdin, an Akt substrate, has been reported to promote tumorigenesis in various tumors. However, the role of Girdin in a spontaneous tumor model has not yet been explored. Here, we studied the role of Girdin in lung adenocarcinoma (LUAD) using the autochthonous mouse model and found that Girdin led...

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Bibliographic Details
Main Authors: Fuyang Cao, Desong Yang, Feiyu Tang, Can Lu, Xiang He, Songming Chen, Zhanghuan Yang, Siyuan Gong, Lunquan Sun, Atsushi Enomoto, Masahide Takahashi, Liang Weng
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cancers
Subjects:
Girdin
PKM2
tumorigenesis
chemoresistance
LUAD
Online Access:https://www.mdpi.com/2072-6694/14/22/5688

Internet

https://www.mdpi.com/2072-6694/14/22/5688

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