Autophagic digestion of Leishmania major by host macrophages is associated with differential expression of BNIP3, CTSE, and the miRNAs miR-101c, miR-129, and miR-210

Autophagic digestion of Leishmania major by host macrophages is associated with differential expression of BNIP3, CTSE, and the miRNAs miR-101c, miR-129, and miR-210

Abstract Background Autophagy participates in innate immunity by eliminating intracellular pathogens. Consequently, numerous microorganisms have developed strategies to impair the autophagic machinery in phagocytes. In the current study, interactions between Leishmania major (L. m.) and the autophag...

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Bibliographic Details
Main Authors: Benjamin Frank, Ana Marcu, Antonio Luis de Oliveira Almeida Petersen, Heike Weber, Christian Stigloher, Jeremy C. Mottram, Claus Juergen Scholz, Uta Schurigt
Format: Article
Language:English
Published: BMC 2015-07-01
Series:Parasites & Vectors
Subjects:
Autophagy
BNIP3
CTSE
Electron tomography
Leishmania major
Macrophages
Online Access:https://doi.org/10.1186/s13071-015-0974-3

Internet

https://doi.org/10.1186/s13071-015-0974-3

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