Pharmacokinetics and Pharmacodynamics of Fungal Defensin NZX Against Staphylococcus aureus-Induced Mouse Peritonitis Model

Pharmacokinetics and Pharmacodynamics of Fungal Defensin NZX Against Staphylococcus aureus-Induced Mouse Peritonitis Model

Staphylococcus aureus (S. aureus) is one of the most common pathogenic bacteria responsible for causing a life-threatening peritonitis disease. NZX, as a variant of fungal defensin plectasin, displayed potent antibacterial activity against S. aureus. In this study, the antibacterial and resistance c...

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Bibliographic Details
Main Authors: Xueling Zheng, Na Yang, Ruoyu Mao, Ya Hao, Da Teng, Jianhua Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Microbiology
Subjects:
fungal defensin NZX
Staphylococcus aureus
intracellular bactericidal activity
pharmacokinetics
pharmacodynamics
mouse peritonitis model
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.865774/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2022.865774/full

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