Mannan-Binding Lectin Reduces Epithelial-Mesenchymal Transition in Pulmonary Fibrosis via Inactivating the Store-Operated Calcium Entry Machinery

Mannan-Binding Lectin Reduces Epithelial-Mesenchymal Transition in Pulmonary Fibrosis via Inactivating the Store-Operated Calcium Entry Machinery

Idiopathic pulmonary fibrosis (IPF) is a type of idiopathic interstitial pneumonia with a poor clinical prognosis. Increasing evidence has demonstrated that epithelial-mesenchymal transition (EMT) contributes to the production of pathogenic myofibroblasts and plays a pivotal role in the development...

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Bibliographic Details
Main Authors: Yunzhi Liu, Xianghuan Xie, Ping Wang, Jialiang Luo, Yu Chen, Qishan Xu, Jia Zhou, Xiao Lu, Jianbo Zhao, Zhengliang Chen, Daming Zuo
Format: Article
Language:English
Published: Karger Publishers 2022-06-01
Series:Journal of Innate Immunity
Subjects:
idiopathic pulmonary fibrosis
mannan-binding lectin
epithelial-mesenchymal transition
store-operated calcium entry
pdk1
Online Access:https://www.karger.com/Article/FullText/524693

Internet

https://www.karger.com/Article/FullText/524693

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