Dose-response in the peripheral analgesic activity of metformin in the abdominal writhing test in mice

Objective: To evaluate the dose-response analgesic effect of metformin in an acute pain event in rodents. Materials and methods: Eighty (80) mice were used. The analgesic effect was evaluated using the abdominal writhing test in mice. Eight (8) groups of 10 mice each were formed: one diclofenac 8...

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Bibliographic Details
Main Authors: Lujan-Carpio E, Pante-Medina C, Salazar-Granara A
Format: Article
Language:Spanish
Published: Universidad de San Martín de Porres 2018-02-01
Series:Horizonte Médico
Subjects:
Online Access:http://www.horizontemedicina.usmp.edu.pe/index.php/horizontemed/article/view/823/470