Statistical Validation of Risk Alleles in Genetic Addiction Risk Severity (GARS) Test: Early Identification of Risk for Alcohol Use Disorder (AUD) in 74,566 Case–Control Subjects

Statistical Validation of Risk Alleles in Genetic Addiction Risk Severity (GARS) Test: Early Identification of Risk for Alcohol Use Disorder (AUD) in 74,566 Case–Control Subjects

Since 1990, when our laboratory published the association of the DRD2 Taq A1 allele and severe alcoholism in <i>JAMA</i>, there has been an explosion of genetic candidate association studies, including GWAS. To develop an accurate test to help identify those at risk for at least Alcohol...

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Bibliographic Details
Main Authors: Kenneth Blum, David Han, Ashim Gupta, David Baron, Eric R. Braverman, Catherine A. Dennen, Shan Kazmi, Luis Llanos-Gomez, Rajendra D. Badgaiyan, Igor Elman, Panayotis K. Thanos, Bill W. Downs, Debasis Bagchi, Marjorie C. Gondre-Lewis, Mark S. Gold, Abdalla Bowirrat
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Journal of Personalized Medicine
Subjects:
statistical validation of GARS
neurotransmitters
dopamine
opioids
odds ratios
Genetic Addiction Risk Severity (GARS)
Online Access:https://www.mdpi.com/2075-4426/12/9/1385

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https://www.mdpi.com/2075-4426/12/9/1385

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