BML-111 inhibit H2O2-induced pyroptosis and osteogenic dysfunction of human periodontal ligament fibroblasts by activating the Nrf2/HO-1 pathway
Abstract Background Periodontitis is a common and harmful chronic inflammatory oral disease, characterized by the destruction of periodontal soft and hard tissues. The NLRP3 inflammasome-related pyroptosis and human periodontal ligament fibroblasts (hPDLFs) osteogenic dysfunction are involved in its...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-01-01
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Series: | BMC Oral Health |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12903-023-03827-w |