The androgen receptor can signal through Wnt/β-Catenin in prostate cancer cells as an adaptation mechanism to castration levels of androgens

<p>Abstract</p> <p>Background</p> <p>A crucial event in Prostate Cancer progression is the conversion from a hormone-sensitive to a hormone-refractory disease state. Correlating with this transition, androgen receptor (AR) amplification and mutations are often observed...

Full description

Bibliographic Details
Main Authors: Lin Tai-An, Wu Qiuyan, Platero J Suso, Spires Thomas E, Rizzo Cheryl A, Schweizer Liang, Gottardis Marco M, Attar Ricardo M
Format: Article
Language:English
Published: BMC 2008-01-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/9/4