Endothelial ERα promotes glucose tolerance by enhancing endothelial insulin transport to skeletal muscle

Abstract The estrogen receptor (ER) designated ERα has actions in many cell and tissue types that impact glucose homeostasis. It is unknown if these include mechanisms in endothelial cells, which have the potential to influence relative obesity, and processes in adipose tissue and skeletal muscle th...

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Main Authors: Anastasia Sacharidou, Ken Chambliss, Jun Peng, Jose Barrera, Keiji Tanigaki, Katherine Luby-Phelps, İpek Özdemir, Sohaib Khan, Shashank R. Sirsi, Sung Hoon Kim, Benita S. Katzenellenbogen, John A. Katzenellenbogen, Mohammed Kanchwala, Adwait A. Sathe, Andrew Lemoff, Chao Xing, Kenneth Hoyt, Chieko Mineo, Philip W. Shaul
格式: 文件
语言:English
出版: Nature Portfolio 2023-08-01
丛编:Nature Communications
在线阅读:https://doi.org/10.1038/s41467-023-40562-w