SPACIA1/SAAL1 Deletion Results in a Moderate Delay in Collagen-Induced Arthritis Activity, along with mRNA Decay of <i>Cyclin-dependent Kinase 6</i> Gene

SPACIA1/SAAL1 Deletion Results in a Moderate Delay in Collagen-Induced Arthritis Activity, along with mRNA Decay of <i>Cyclin-dependent Kinase 6</i> Gene

This study was performed to elucidate the molecular function of the synoviocyte proliferation-associated in collagen-induced arthritis (CIA) 1/serum amyloid A-like 1 (SPACIA1/SAAL1) in mice CIA, an animal model of rheumatoid arthritis (RA), and human RA-synovial fibroblasts (RASFs). <i>SPACIA1...

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Bibliographic Details
Main Authors: Ryoji Fujii, Rie Komatsu, Tomoo Sato, Iwao Seki, Koji Konomi, Hiroyuki Aono, Hisateru Niki, Kazuo Yudoh, Kusuki Nishioka, Toshihiro Nakajima
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:International Journal of Molecular Sciences
Subjects:
cell cycle
collagen-induced arthritis
cyclin-dependent kinase
proliferation
rheumatoid arthritis
synovitis
Online Access:https://www.mdpi.com/1422-0067/19/12/3828

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https://www.mdpi.com/1422-0067/19/12/3828

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