Identification of differentially methylated genes in first-trimester placentas with trisomy 16

Identification of differentially methylated genes in first-trimester placentas with trisomy 16

Abstract The presence of an extra chromosome in the embryo karyotype often dramatically affects the fate of pregnancy. Trisomy 16 is the most common aneuploidy in first-trimester miscarriages. The present study identified changes in DNA methylation in chorionic villi of miscarriages with trisomy 16....

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Main Authors: Ekaterina N. Tolmacheva, Stanislav A. Vasilyev, Tatiana V. Nikitina, Ekaterina S. Lytkina, Elena A. Sazhenova, Daria I. Zhigalina, Oksana Yu. Vasilyeva, Anton V. Markov, Victoria V. Demeneva, Liubov A. Tashireva, Anna A. Kashevarova, Igor N. Lebedev
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-04107-9

Internet

https://doi.org/10.1038/s41598-021-04107-9

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