Differential Uridyl-diphosphate-Glucuronosyl Transferase 1A enzymatic arsenal explains the specific cytotoxicity of resveratrol towards tumor colorectal cells

Differential Uridyl-diphosphate-Glucuronosyl Transferase 1A enzymatic arsenal explains the specific cytotoxicity of resveratrol towards tumor colorectal cells

Resveratrol belongs to the Bioactive Food Component (BFC) family. It seems admitted that its cytotoxic action impacts tumor cells and spares healthy cells, but the published proofs remain rare. We hypothesized that cells may differentially metabolize resveratrol and lead to different systemic impact...

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Bibliographic Details
Main Authors: Samuel Amintas, Pauline Beaumont, Charles Dupin, Isabelle Moranvillier, Isabelle Lamrissi, Elie Patel, Benjamin Fernandez, Alice Bibeyran, Julian Boutin, Tristan Richard, Stéphanie Krisa, François Moreau-Gaudry, Aurélie Bedel, David Cappellen, Benoît Pinson, Véronique Vendrely, Sandrine Dabernat
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Journal of Functional Foods
Subjects:
Bioactive food components
UGT
Drug sensitivity
Colorectal cancer
Tumorigenesis
Nucleotide metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464622004157

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http://www.sciencedirect.com/science/article/pii/S1756464622004157

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