Deletion of nardilysin prevents the development of steatohepatitis and liver fibrotic changes.

Deletion of nardilysin prevents the development of steatohepatitis and liver fibrotic changes.

Nonalcoholic steatohepatitis (NASH) is an inflammatory form of nonalcoholic fatty liver disease that progresses to liver cirrhosis. It is still unknown how only limited patients with fatty liver develop NASH. Tumor necrosis factor (TNF)-α is one of the key molecules in initiating the vicious circle...

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Main Authors: Shoko Ishizu-Higashi, Hiroshi Seno, Eiichiro Nishi, Yoshihide Matsumoto, Kozo Ikuta, Motoyuki Tsuda, Yoshito Kimura, Yutaka Takada, Yuto Kimura, Yuki Nakanishi, Keitaro Kanda, Hideyuki Komekado, Tsutomu Chiba
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4029810?pdf=render

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http://europepmc.org/articles/PMC4029810?pdf=render

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