Immune defects associated with lower SARS-CoV-2 BNT162b2 mRNA vaccine response in aged people

The immune factors associated with impaired SARS-CoV-2 vaccine response in elderly people are mostly unknown. We studied individuals older than 60 and younger than 60 years, who had been vaccinated with SARS-CoV-2 BNT162b2 mRNA, before and after the first and second dose. Aging was associated with a...

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Bibliographic Details
Main Authors: Joana Vitallé, Alberto Pérez-Gómez, Francisco José Ostos, Carmen Gasca-Capote, María Reyes Jiménez-León, Sara Bachiller, Inmaculada Rivas-Jeremías, Maria del Mar Silva-Sánchez, Anabel M. Ruiz-Mateos, María Ángeles Martín-Sánchez, Luis Fernando López-Cortes, Mohammed Rafii-El-Idrissi Benhnia, Ezequiel Ruiz-Mateos
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-09-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.161045