Engineering Skeletal Muscle Grafts with PAX7::GFP-Sorted Human Pluripotent Stem Cell-Derived Myogenic Progenitors on Fibrin Microfiber Bundles for Tissue Regeneration

Engineering Skeletal Muscle Grafts with PAX7::GFP-Sorted Human Pluripotent Stem Cell-Derived Myogenic Progenitors on Fibrin Microfiber Bundles for Tissue Regeneration

Tissue engineering strategies that combine human pluripotent stem cell-derived myogenic progenitors (hPDMs) with advanced biomaterials provide promising tools for engineering 3D skeletal muscle grafts to model tissue development in vitro and promote muscle regeneration in vivo. We recently demonstra...

Full description

Bibliographic Details
Main Authors: Sarah M. Somers, Jordana Gilbert-Honick, In Young Choi, Emily K. W. Lo, HoTae Lim, Shaquielle Dias, Kathryn R. Wagner, Hai-Quan Mao, Patrick Cahan, Gabsang Lee, Warren L. Grayson
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Bioengineering
Subjects:
human pluripotent stem cells (hPSCs)
hPSC-derived myogenic progenitors (hPDMs) PAX7
skeletal muscle tissue engineering
skeletal muscle injury and regeneration
fibrin microfiber bundles
Online Access:https://www.mdpi.com/2306-5354/9/11/693

Internet

https://www.mdpi.com/2306-5354/9/11/693

Similar Items