Indoleamine 2,3-Dioxygenase and Tolerance: Where Are We Now?
Cells expressing IDO suppress innate and adaptive immunity to promote tolerance by catabolizing the amino acid tryptophan (Trp) and other indole compounds. Interferon type I (IFN-I) and type II (IFN-II) produced at sites of inflammation or by activated immune cells are potent IDO inducers because ma...
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| Fformat: | Erthygl |
| Iaith: | English |
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Frontiers Media S.A.
2017-10-01
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| Cyfres: | Frontiers in Immunology |
| Pynciau: | |
| Mynediad Ar-lein: | http://journal.frontiersin.org/article/10.3389/fimmu.2017.01360/full |