Indoleamine 2,3-Dioxygenase and Tolerance: Where Are We Now?
Cells expressing IDO suppress innate and adaptive immunity to promote tolerance by catabolizing the amino acid tryptophan (Trp) and other indole compounds. Interferon type I (IFN-I) and type II (IFN-II) produced at sites of inflammation or by activated immune cells are potent IDO inducers because ma...
| Päätekijät: | , , |
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| Aineistotyyppi: | Artikkeli |
| Kieli: | English |
| Julkaistu: |
Frontiers Media S.A.
2017-10-01
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| Sarja: | Frontiers in Immunology |
| Aiheet: | |
| Linkit: | http://journal.frontiersin.org/article/10.3389/fimmu.2017.01360/full |