Synthesis of N-7-Substituted Purines from Imidazole Precursors
Synthesis of purines and purine mono-1-oxides from the respective 5-substituted 4-nitroimidazole derivatives is described. The commercially available 4-nitroimidazole, in a few simple steps (including Vicarious Nucleophilic Substitution of Hydrogen), was transformed into: 4-aminoimidazoyl-5-carboxim...
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| Format: | Article |
| Language: | English |
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MDPI AG
1999-09-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/4/10/287/ |