The Interaction between hERG1 and β1 Integrins Modulates hERG1 Current in Different Pathological Cell Models

The Interaction between hERG1 and β1 Integrins Modulates hERG1 Current in Different Pathological Cell Models

Ion channels are implicated in various diseases, including cancer, in which they modulate different aspects of cancer progression. In particular, potassium channels are often aberrantly expressed in cancers, a major example being provided by hERG1. The latter is generally complexed with β1 integrin...

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Bibliographic Details
Main Authors: Ginevra Chioccioli Altadonna, Alberto Montalbano, Jessica Iorio, Andrea Becchetti, Annarosa Arcangeli, Claudia Duranti
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Membranes
Subjects:
hERG1
adhesion molecules
ion channels
fibronectin
macromolecular complexes
ECM proteins
Online Access:https://www.mdpi.com/2077-0375/12/11/1162

Internet

https://www.mdpi.com/2077-0375/12/11/1162

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