A Boron-Containing Analogue of Acetaminophen Induces Analgesic Effect in Hot Plate Test and Limited Hepatotoxicity

A Boron-Containing Analogue of Acetaminophen Induces Analgesic Effect in Hot Plate Test and Limited Hepatotoxicity

Acetaminophen is the most sold drug to treat pain. The TRPV1 channel is among its main targets. Due to its over-the-counter availability, its use is known as the main cause of acute liver failure induced by drugs. In addition, boron-containing compounds (BCC) have shown higher efficiency, potency, a...

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Bibliographic Details
Main Authors: Melvin Nadir Rosalez, Eunice D. Farfán-García, Jesús Badillo-Romero, Ricardo Iván Córdova-Chávez, José G. Trujillo-Ferrara, José A. Morales-González, Marvin A. Soriano-Ursúa, Marlet Martínez-Archundia
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Inorganics
Subjects:
acetaminophen
boron
pain
analgesia
TRPV
hepatotoxicity
Online Access:https://www.mdpi.com/2304-6740/11/6/261

Internet

https://www.mdpi.com/2304-6740/11/6/261

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