Sterol synthesis : chemical synthesis of 3 beta-hydroxy-5 alpha-cholest-7-ene-9 alpha-carbonitrile.

3 beta-Hydroxy-5 alpha-cholest-7-ene-9 alpha-carbonitrile was obtained via hydrocyanation of 3 beta-acetoxy-5 alpha-cholest-8-en-7-one by diethylaluminum cyanide. The resulting 9 alpha-cyano-7-ketone was reduced with sodium borohydride to 7 alpha-hydroxy-compound. These compounds were characterized...

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Bibliographic Details
Main Authors: M Anastasia, P Allevi
Format: Article
Language:English
Published: Elsevier 1981-02-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520353797