Functional validation of novel levamisole resistance marker S168T in Haemonchus contortus
Recently, a S168T variant in the acetylcholine receptor subunit ACR-8 was associated with levamisole resistance in the parasitic helminth Haemonchus contortus. Here, we used the Xenopus laevis oocyte expression system and two-electrode voltage-clamp electrophysiology to measure the functional impact...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-04-01
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Series: | International Journal for Parasitology: Drugs and Drug Resistance |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211320724000058 |