Limiting glucocorticoid secretion increases the anorexigenic property of Exendin-4

Limiting glucocorticoid secretion increases the anorexigenic property of Exendin-4

Objective: Glucagon-like peptide-1 (GLP-1) analogs are attractive options for the treatment of type II diabetes and obesity because of their incretin and anorexigenic effects. Peripheral administration of the GLP-1R agonist Exendin-4 (Ex-4) also increases glucocorticoid secretion in rodents and huma...

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Bibliographic Details
Main Authors: Shin J. Lee, Katharina Diener, Sharon Kaufman, Jean-Philippe Krieger, Klaus G. Pettersen, Nino Jejelava, Myrtha Arnold, Alan G. Watts, Wolfgang Langhans
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877816300321

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http://www.sciencedirect.com/science/article/pii/S2212877816300321

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