Quantifying Genomic Imprinting at Tissue and Cell Resolution in the Brain

Imprinted genes are a group of ~150 genes that are preferentially expressed from one parental allele owing to epigenetic marks asymmetrically distributed on inherited maternal and paternal chromosomes. Altered imprinted gene expression causes human brain disorders such as Prader-Willi and Angelman s...

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Bibliographic Details
Main Authors: Annie Varrault, Emeric Dubois, Anne Le Digarcher, Tristan Bouschet
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Epigenomes
Subjects:
Online Access:https://www.mdpi.com/2075-4655/4/3/21