Differential whole-genome doubling based signatures for improvement on clinical outcomes and drug response in patients with breast cancer

Whole genome doublings (WGD), a hallmark of human cancer, is pervasive in breast cancer patients. However, the molecular mechanism of the complete impact of WGD on survival and treatment response in breast cancer remains unclear. To address this, we performed a comprehensive and systematic analysis...

Full description

Bibliographic Details
Main Authors: Yingli Lv, Guotao Feng, Lei Yang, Xiaoliang Wu, Chengyi Wang, Aokun Ye, Shuyuan wang, Chaohan Xu, Hongbo Shi
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024046176