First Human Leucocyte Antigen (HLA) Response and Safety Evaluation of Fibrous Demineralized Bone Matrix in a Critical Size Femoral Defect Model of the Sprague-Dawley Rat

First Human Leucocyte Antigen (HLA) Response and Safety Evaluation of Fibrous Demineralized Bone Matrix in a Critical Size Femoral Defect Model of the Sprague-Dawley Rat

Treatment of large bone defects is one of the great challenges in contemporary orthopedic and traumatic surgery. Grafts are necessary to support bone healing. A well-established allograft is demineralized bone matrix (DBM) prepared from donated human bone tissue. In this study, a fibrous demineraliz...

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Bibliographic Details
Main Authors: Nicolas Söhling, Maximilian Leiblein, Alexander Schaible, Maren Janko, Joachim Schwäble, Christian Seidl, Jan C. Brune, Christoph Nau, Ingo Marzi, Dirk Henrich, René D. Verboket
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Materials
Subjects:
demineralized bone matrix
rat femur critical size defect
Online Access:https://www.mdpi.com/1996-1944/13/14/3120

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https://www.mdpi.com/1996-1944/13/14/3120

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