Deep reinforcement learning-based pairwise DNA sequence alignment method compatible with embedded edge devices

Abstract Sequence alignment is an essential component of bioinformatics, for identifying regions of similarity that may indicate functional, structural, or evolutionary relationships between the sequences. Genome-based diagnostics relying on DNA sequencing have benefited hugely from the boom in comp...

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Bibliographic Details
Main Authors: Aryan Lall, Siddharth Tallur
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-29277-6