Rifampicin Resistance: Fitness Costs and the Significance of Compensatory Evolution

Seventy years after the introduction of antibiotic chemotherapy to treat tuberculosis, problems caused by drug-resistance in Mycobacterium tuberculosis have become greater than ever. The discovery and development of novel drugs and drug combination therapies will be critical to managing these proble...

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Detalhes bibliográficos
Main Authors: Gerrit Brandis, Diarmaid Hughes
Formato: Artigo
Idioma:English
Publicado em: MDPI AG 2013-04-01
Colecção:Antibiotics
Assuntos:
Acesso em linha:http://www.mdpi.com/2079-6382/2/2/206