Single-cell RNA-seq highlights heterogeneity in human primary Wharton’s jelly mesenchymal stem/stromal cells cultured in vitro

Single-cell RNA-seq highlights heterogeneity in human primary Wharton’s jelly mesenchymal stem/stromal cells cultured in vitro

Abstract Background Mesenchymal stem/stromal cells (MSCs) are multipotent cells with a promising application potential in regenerative medicine and immunomodulation. However, MSCs cultured in vitro exhibit functional heterogeneity. The underlying molecular mechanisms that define MSC heterogeneity re...

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Bibliographic Details
Main Authors: Changbin Sun, Lei Wang, Hailun Wang, Tingrun Huang, Wenwen Yao, Jing Li, Xi Zhang
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Stem Cell Research & Therapy
Subjects:
MSCs
scRNA-seq
Highly variable genes
Functional enrichment
Potency
Online Access:http://link.springer.com/article/10.1186/s13287-020-01660-4

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http://link.springer.com/article/10.1186/s13287-020-01660-4

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