SHTXTHHly, an extracellular secretion platform for the preparation of bioactive peptides and proteins in Escherichia coli

SHTXTHHly, an extracellular secretion platform for the preparation of bioactive peptides and proteins in Escherichia coli

Abstract Background In previous work, we developed an E. coli extracellular secretion platform XTHHly based on the hemolysin A secretion system. It can produce bioactive peptides with simple purification procedures. However, the wider application of this platform is limited by poor secretion efficie...

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Bibliographic Details
Main Authors: Wen Zhu, Yang Wang, Liangyin Lv, Hui Wang, Wenqiang Shi, Zexin Liu, Wei Yang, Jianwei Zhu, Huili Lu
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Microbial Cell Factories
Subjects:
Hemolysin A
E. coli
Secretory expression
S tag
Rapid bioactivity detection
Online Access:https://doi.org/10.1186/s12934-022-01856-8

Internet

https://doi.org/10.1186/s12934-022-01856-8

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